Smart Insulin

[skb]

The UCLA is working on a smart insulin known as i-insulin, which is responsive to the glucose levels in the body, thereby reducing the chances of hypoglycemic events.

Inside the body, insulin acts as a "key" to help glucose get into cells from the bloodstream. When insulin attaches to a cell's surface, it activates a protein inside the cell, called glucose transporter, which then makes its way to the cell's surface. This molecule then brings the surrounding glucose from the blood into the cell.

The research team added an additional molecule to insulin to create the new smart insulin. This added molecule, called a glucose transporter inhibitor, chemically blocks the glucose transporter molecule that has come to the surface. Its presence doesn't block all glucose from entering, nor does it permanently block the transporter molecules. Instead, it's part of a dynamic process that depends on how many inhibitor and glucose molecules are present.

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[Javar]

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