Reversing new-onset type 1 diabetes with pyramid-like DNA

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Usually diagnosed in children, teens and young adults, type 1 diabetes is an autoimmune disease in which the immune system attacks and destroys insulin-secreting β-cells in the pancreas. As a result, people with type 1 diabetes can't regulate their blood sugar levels and require insulin treatment for survival. Now, researchers reporting in ACS Applied Materials & Interfaces have reversed new-onset type 1 diabetes in mice with pyramid-like DNA molecules called tetrahedral framework nucleic acids (tFNAs).

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