Protein responsible for T1 detected

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The multidisciplinary research team of physicians and biochemists used a new strategy to pinpoint proteins in beta cells, a subset of pancreatic islets that increase or decrease in response to immune system attack. Beta cells normally regulate blood sugar levels in the pancreas. In people susceptible to type 1 diabetes (previously called insulin-dependent or juvenile diabetes) these cells are slowly destroyed by the body's own immune system. Here, the researchers focused on how islets respond to inflammation.

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As noted in other answers, a common mode of dominant vs. recessive alleles is that the wild-type allele is dominant and encodes a functional protein; the recessive allele is a mutant and encodes a less functional or non-functional protein.
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